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Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data

To detect functional somatic mutations in tumor samples, whole-exome sequencing (WES) is often used for its reliability and relative low cost. RNA-seq, while generally used to measure gene expression, can potentially also be used for identification of somatic mutations. However there has been little...

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Detalles Bibliográficos
Autores principales: Coudray, Alexandre, Battenhouse, Anna M., Bucher, Philipp, Iyer, Vishwanath R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074801/
https://www.ncbi.nlm.nih.gov/pubmed/30083469
http://dx.doi.org/10.7717/peerj.5362