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Identifying a missing lineage driver in a subset of lung neuroendocrine tumors

Tumor heterogeneity of a primary histologic cancer type has major implications for cancer research and therapeutics. An important and understudied aspect of this heterogeneity is the role of transcription factors that serve as “lineage oncogenes” in a tumor type. A demonstration that different subgr...

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Detalles Bibliográficos
Autores principales: Pozo, Karine, Minna, John D., Johnson, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075039/
https://www.ncbi.nlm.nih.gov/pubmed/29967289
http://dx.doi.org/10.1101/gad.316943.118