Hybrid complexes of high and low molecular weight hyaluronan delay in vitro replicative senescence of mesenchymal stromal cells: a pilot study for future therapeutic application

Mesenchymal stem cells, a subpopulation of mesenchymal stromal cells (MSCs), are present in the stroma of several tissues. MSC in vitro cultivation for clinical treatments may greatly affect MSC properties. A primary handicap is replicative senescence that impairs MSC functions. Hyaluronan (HA) is p...

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Detalles Bibliográficos
Autores principales: Alessio, Nicola, Stellavato, Antonietta, Squillaro, Tiziana, Del Gaudio, Stefania, Di Bernardo, Giovanni, Peluso, Gianfranco, De Rosa, Mario, Schiraldi, Chiara, Galderisi, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075440/
https://www.ncbi.nlm.nih.gov/pubmed/30001217
http://dx.doi.org/10.18632/aging.101493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075440/
https://www.ncbi.nlm.nih.gov/pubmed/30001217
http://dx.doi.org/10.18632/aging.101493

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