Nicotine exposure impairs germ cell development in human fetal ovaries cultured in vitro

In the present paper, we found that human fetal ovaries (at ~16 weeks) express the transcripts for several subunits of the nicotinic acetylcholine receptor (nAChR). Exposure to the drug in vitro resulted in the marked increase of apoptosis in the ovaries in a time and dose-dependent manner. Evidence...

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Detalles Bibliográficos
Autores principales: Cheng, Shun-Feng, Qin, Xun-Si, Han, Ze-Li, Sun, Xiao-Feng, Feng, Yan-Ni, Yang, Fan, Ge, Wei, Li, Lan, Zhao, Yong, De Felici, Massimo, Zou, Shu-Hua, Zhou, Yi, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075447/
https://www.ncbi.nlm.nih.gov/pubmed/30001218
http://dx.doi.org/10.18632/aging.101492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075447/
https://www.ncbi.nlm.nih.gov/pubmed/30001218
http://dx.doi.org/10.18632/aging.101492

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