Cargando…

Caloric restriction effects on liver mTOR signaling are time-of-day dependent

The regulation of mechanistic target of rapamycin (mTOR) signaling contributes to the metabolic effects of a calorie restriction (CR) diet. We assayed the effect of CR on the activity of mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2) in the liver of mice at six different times across the day. C...

Descripción completa

Detalles Bibliográficos
Autores principales: Tulsian, Richa, Velingkaar, Nikkhil, Kondratov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075448/
https://www.ncbi.nlm.nih.gov/pubmed/30018180
http://dx.doi.org/10.18632/aging.101498