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FusionPathway: Prediction of pathways and therapeutic targets associated with gene fusions in cancer

Numerous gene fusions have been uncovered across multiple cancer types. Although the ability to target several of these fusions has led to the development of some successful anti-cancer drugs, most of them are not druggable. Understanding the molecular pathways of a fusion is important in determinin...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Chin, Beird, Hannah C., Zhang, Jianhua, Futreal, P. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075785/
https://www.ncbi.nlm.nih.gov/pubmed/30040819
http://dx.doi.org/10.1371/journal.pcbi.1006266