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Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review

BACKGROUND: Metformin is one of the most commonly used drugs for the treatment of type 2 diabetes mellitus (T2DM). Despite its widespread use, there are considerable interindividual variations in metformin response, with about 35% of patients failing to achieve initial glycemic control. These variab...

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Detalles Bibliográficos
Autores principales: Mofo Mato, Edith Pascale, Guewo-Fokeng, Magellan, Essop, M. Faadiel, Owira, Peter Mark Oroma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076123/
https://www.ncbi.nlm.nih.gov/pubmed/29979413
http://dx.doi.org/10.1097/MD.0000000000011349