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Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review
BACKGROUND: Metformin is one of the most commonly used drugs for the treatment of type 2 diabetes mellitus (T2DM). Despite its widespread use, there are considerable interindividual variations in metformin response, with about 35% of patients failing to achieve initial glycemic control. These variab...
Autores principales: | Mofo Mato, Edith Pascale, Guewo-Fokeng, Magellan, Essop, M. Faadiel, Owira, Peter Mark Oroma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076123/ https://www.ncbi.nlm.nih.gov/pubmed/29979413 http://dx.doi.org/10.1097/MD.0000000000011349 |
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