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High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial
BACKGROUND: Glioblastoma multiforme (GBM) is a rare and deadly disease, with a reported average incidence rate of 3.19 cases per 100,000 inhabitants. Fotemustine, a third-generation nitrosourea with an alanine phosphor carrier that facilitates cellular penetration, has been extensively investigated...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076126/ https://www.ncbi.nlm.nih.gov/pubmed/29979390 http://dx.doi.org/10.1097/MD.0000000000011254 |