Cargando…

Reciprocal Perspective for Improved Protein-Protein Interaction Prediction

All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating positive PPIs from negatives. Historically, a single global threshold, typically optimized via cross-validation testing, is applied to all protein pairs. However, we h...

Descripción completa

Detalles Bibliográficos
Autores principales: Dick, Kevin, Green, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076239/
https://www.ncbi.nlm.nih.gov/pubmed/30076341
http://dx.doi.org/10.1038/s41598-018-30044-1