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Reciprocal Perspective for Improved Protein-Protein Interaction Prediction
All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating positive PPIs from negatives. Historically, a single global threshold, typically optimized via cross-validation testing, is applied to all protein pairs. However, we h...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076239/ https://www.ncbi.nlm.nih.gov/pubmed/30076341 http://dx.doi.org/10.1038/s41598-018-30044-1 |