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Reciprocal Perspective for Improved Protein-Protein Interaction Prediction

All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating positive PPIs from negatives. Historically, a single global threshold, typically optimized via cross-validation testing, is applied to all protein pairs. However, we h...

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Detalles Bibliográficos
Autores principales:	Dick, Kevin, Green, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076239/ https://www.ncbi.nlm.nih.gov/pubmed/30076341 http://dx.doi.org/10.1038/s41598-018-30044-1

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