Establishing normal metabolism and differentiation in hepatocellular carcinoma cells by culturing in adult human serum

Tissue culture medium routinely contains fetal bovine serum (FBS). Here we show that culturing human hepatoma cells in their native, adult serum (human serum, HS) results in the restoration of key morphological and metabolic features of normal liver cells. When moved to HS, these cells show differen...

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Detalles Bibliográficos
Autores principales: Steenbergen, Rineke, Oti, Martin, ter Horst, Rob, Tat, Wilson, Neufeldt, Chris, Belovodskiy, Alexandr, Chua, Tiing Tiing, Cho, Woo Jung, Joyce, Michael, Dutilh, Bas E., Tyrrell, D. Lorne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076254/
https://www.ncbi.nlm.nih.gov/pubmed/30076349
http://dx.doi.org/10.1038/s41598-018-29763-2

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