A widespread alternate form of cap-dependent mRNA translation initiation

Translation initiation of most mammalian mRNAs is mediated by a 5′ cap structure that binds eukaryotic initiation factor 4E (eIF4E). However, inactivation of eIF4E does not impair translation of many capped mRNAs, suggesting an unknown alternate mechanism may exist for cap-dependent but eIF4E-indepe...

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Detalles Bibliográficos
Autores principales: de la Parra, Columba, Ernlund, Amanda, Alard, Amandine, Ruggles, Kelly, Ueberheide, Beatrix, Schneider, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076257/
https://www.ncbi.nlm.nih.gov/pubmed/30076308
http://dx.doi.org/10.1038/s41467-018-05539-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076257/
https://www.ncbi.nlm.nih.gov/pubmed/30076308
http://dx.doi.org/10.1038/s41467-018-05539-0

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