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Diosgenin restores Aβ-induced axonal degeneration by reducing the expression of heat shock cognate 70 (HSC70)
We previously found diosgenin, an herbal drug-derived steroid sapogenin, to be remarkably effective at restoring Aβ-induced axonal degeneration and improving memory function in model of Alzheimer’s disease (AD), 5XFAD mouse. In this study, we investigated the downstream signaling of diosgenin and ex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076317/ https://www.ncbi.nlm.nih.gov/pubmed/30076345 http://dx.doi.org/10.1038/s41598-018-30102-8 |