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A modified gene trap approach for improved high-throughput cancer drug discovery

While advances in laboratory automation have dramatically increased throughput of compound screening efforts, development of robust cell-based assays in relevant disease models remain resource-intensive and time-consuming, presenting a bottleneck to drug discovery campaigns. To address this issue, w...

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Detalles Bibliográficos
Autores principales: Morris, Shelli M., Mhyre, Andrew J., Carmack, Savanna S., Myers, Carrie H., Burns, Connor, Ye, Wenjuan, Ferrer, Marc, Olson, James M., Klinghoffer, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076322/
https://www.ncbi.nlm.nih.gov/pubmed/29717260
http://dx.doi.org/10.1038/s41388-018-0274-4