Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure

Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease and a major health problem in the United States. While the cytokine TGF-β has been implicated in PDAC development, it can exert both pro- and anti-tumorigenic effects that are highly context dependent and incompletely understood. Using thre...

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Detalles Bibliográficos
Autores principales: Handler, Jesse, Cullis, Jane, Avanzi, Antonina, Vucic, Emily A., Bar-Sagi, Dafna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076343/
https://www.ncbi.nlm.nih.gov/pubmed/29713060
http://dx.doi.org/10.1038/s41388-018-0264-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076343/
https://www.ncbi.nlm.nih.gov/pubmed/29713060
http://dx.doi.org/10.1038/s41388-018-0264-6

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