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Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease and a major health problem in the United States. While the cytokine TGF-β has been implicated in PDAC development, it can exert both pro- and anti-tumorigenic effects that are highly context dependent and incompletely understood. Using thre...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076343/ https://www.ncbi.nlm.nih.gov/pubmed/29713060 http://dx.doi.org/10.1038/s41388-018-0264-6 |