Improving knowledge on the activation of bone marrow fibroblasts in MGUS and MM disease through the automatic extraction of genes via a nonnegative matrix factorization approach on gene expression profiles

BACKGROUND: Multiple myeloma (MM) is a cancer of terminally differentiated plasma that is part of a spectrum of blood diseases. The role of the micro-environment is crucial for MM clonal evolution. METHODS: This paper describes the analysis carried out on a limited number of genes automatically extr...

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Detalles Bibliográficos
Autores principales: Boccarelli, Angelina, Esposito, Flavia, Coluccia, Mauro, Frassanito, Maria Antonia, Vacca, Angelo, Del Buono, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076394/
https://www.ncbi.nlm.nih.gov/pubmed/30075788
http://dx.doi.org/10.1186/s12967-018-1589-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076394/
https://www.ncbi.nlm.nih.gov/pubmed/30075788
http://dx.doi.org/10.1186/s12967-018-1589-1

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