Genetic and genomic stability across lymphoblastoid cell line expansions

OBJECTIVE: Lymphoblastoid cell lines are widely used in genetic and genomic studies. Previous work has characterized variant stability in transformed culture and across culture passages. Our objective was to extend this work to evaluate single nucleotide polymorphism and structural variation across...

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Detalles Bibliográficos
Autores principales: Scheinfeldt, Laura B., Hodges, Kelly, Pevsner, Jonathan, Berlin, Dorit, Turan, Nahid, Gerry, Norman P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076395/
https://www.ncbi.nlm.nih.gov/pubmed/30075799
http://dx.doi.org/10.1186/s13104-018-3664-3