Gene Modification of Transforming Growth Factor β (TGF-β) and Interleukin 10 (IL-10) in Suppressing Mt Sonicate Induced Osteoclast Formation and Bone Absorption

BACKGROUND: Osteoarticular tuberculosis is an osteolytic lesion caused by Mycobacterium tuberculosis (MTB). Inflammatory factors such as TNF-α play a critical role in anti-tuberculosis immunity by regulating osteoblast and osteoclast functions. Both TGF-β and IL-10 have immune suppression effects to...

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Detalles Bibliográficos
Autores principales: Yi, Lankai, Li, Zhong, Jiang, Housen, Cao, Zhenhao, Liu, Junhua, Zhang, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076426/
https://www.ncbi.nlm.nih.gov/pubmed/30050032
http://dx.doi.org/10.12659/MSM.909720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076426/
https://www.ncbi.nlm.nih.gov/pubmed/30050032
http://dx.doi.org/10.12659/MSM.909720

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