Development of a high throughput yeast-based screening assay for human carbonic anhydrase isozyme II inhibitors

Carbonic anhydrase (CA; EC 4.2.1.1) catalyzes the reversible hydration of carbon dioxide (CO(2)) to bicarbonate and proton. There are 16 known isozymes of α-CA in humans, which differ widely in their kinetics, subcellular localization and tissue-specific distribution. Several disorders are associate...

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Detalles Bibliográficos
Autores principales: Sangkaew, Anyaporn, Krungkrai, Jerapan, Yompakdee, Chulee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076874/
https://www.ncbi.nlm.nih.gov/pubmed/30078153
http://dx.doi.org/10.1186/s13568-018-0653-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076874/
https://www.ncbi.nlm.nih.gov/pubmed/30078153
http://dx.doi.org/10.1186/s13568-018-0653-9

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