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Gemcitabine-Incorporated G-Quadruplex Aptamer for Targeted Drug Delivery into Pancreas Cancer

Gemcitabine has been considered a first-line chemotherapy agent for the treatment of pancreatic cancer. However, the initial response rate of gemcitabine is low and chemoresistance occurs frequently. Aptamers can be effectively internalized into cancer cells via binding to target molecules with high...

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Detalles Bibliográficos
Autores principales: Park, Jun Young, Cho, Ye Lim, Chae, Ju Ri, Moon, Sung Hwan, Cho, Won Gil, Choi, Yun Jung, Lee, Soo Jin, Kang, Won Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077122/
https://www.ncbi.nlm.nih.gov/pubmed/30195790
http://dx.doi.org/10.1016/j.omtn.2018.06.003