Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution

Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA vaccines. With ease of manufacture and biocompatibility in mind, we explored condensation of DNA in aqueous solution with a self-crosslinking,...

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Detalles Bibliográficos
Autores principales: Ho, Joan K., White, Paul J., Pouton, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077166/
https://www.ncbi.nlm.nih.gov/pubmed/30195787
http://dx.doi.org/10.1016/j.omtn.2018.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077166/
https://www.ncbi.nlm.nih.gov/pubmed/30195787
http://dx.doi.org/10.1016/j.omtn.2018.05.025

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