Cargando…

Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution

Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA vaccines. With ease of manufacture and biocompatibility in mind, we explored condensation of DNA in aqueous solution with a self-crosslinking,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho, Joan K., White, Paul J., Pouton, Colin W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077166/ https://www.ncbi.nlm.nih.gov/pubmed/30195787 http://dx.doi.org/10.1016/j.omtn.2018.05.025

Ejemplares similares

Single-Step Self-Assembly and Physical Crosslinking of PEGylated Chitosan Nanoparticles by Tannic Acid
por: Smith, Raven A., et al.
Publicado: (2019)

Assembly of DNA Architectures in a Non-Aqueous Solution
por: Finch, Amethist S., et al.
Publicado: (2012)

Tissue-specific Calibration of Real-time PCR Facilitates Absolute Quantification of Plasmid DNA in Biodistribution Studies
por: Ho, Joan K, et al.
Publicado: (2016)

Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging
por: Lee, Jung Eun, et al.
Publicado: (2018)

Peptide hormones and lipopeptides: from self‐assembly to therapeutic applications
por: Hutchinson, J. A., et al.
Publicado: (2017)

Self-Assembly of a Catalytically Active Lipopeptide and Its Incorporation into Cubosomes
por: Castelletto, Valeria, et al.
Publicado: (2019)

Tunable Self-Assembled Nanostructures of Electroactive PEGylated Tetra(Aniline) Based ABA Triblock Structures in Aqueous Medium
por: Mushtaq, Irrum, et al.
Publicado: (2019)

Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies
por: Diaferia, Carlo, et al.
Publicado: (2016)

DNA- and DNA-Protein-Crosslink Repair in Plants
por: Enderle, Janina, et al.
Publicado: (2019)

Self-Assembly of Soluplus in Aqueous Solutions: Characterization and Prospectives on Perfume Encapsulation
por: Sofroniou, Constantina, et al.
Publicado: (2022)

Effect of Glycosylation on Self-Assembly of Lipid A Lipopolysaccharides in Aqueous Solutions
por: Castelletto, Valeria, et al.
Publicado: (2023)

Crossbar nanoarchitectonics of the crosslinked self-assembled monolayer
por: Hamoudi, Hicham
Publicado: (2014)

Extensins: Self-Assembly, Crosslinking, and the Role of Peroxidases
por: Mishler-Elmore, John W., et al.
Publicado: (2021)

Self-Assembly, Nematic Phase Formation, and Organocatalytic Behavior of a Proline-Functionalized Lipopeptide
por: Pelin, Juliane N.B.D., et al.
Publicado: (2020)

Insights on the DNA Stability in Aqueous Solutions of Ionic Liquids
por: Dinis, Teresa B. V., et al.
Publicado: (2020)

The Assembly of DNA Amphiphiles at Liquid Crystal-Aqueous Interface
por: Zhou, Jingsheng, et al.
Publicado: (2016)

The colibactin warhead crosslinks DNA
por: Vizcaino, Maria I., et al.
Publicado: (2015)

Understanding the Role of Self-Assembly and Interaction with Biological Membranes of Short Cationic Lipopeptides in the Effective Design of New Antibiotics
por: Stachurski, Oktawian, et al.
Publicado: (2022)

Crosslinking Kinetics of Methylcellulose Aqueous Solution and Its Potential as a Scaffold for Tissue Engineering
por: Niemczyk-Soczynska, Beata, et al.
Publicado: (2019)

DNA Penetration into a Lysozyme Layer at the Surface of Aqueous Solutions
por: Chirkov, Nikolay S., et al.
Publicado: (2022)

Mechanical Properties of DNA-Crosslinked Polyacrylamide Hydrogels with Increasing Crosslinker Density
por: Previtera, Michelle L., et al.
Publicado: (2012)

How to fix DNA-protein crosslinks
por: Kühbacher, Ulrike, et al.
Publicado: (2020)

Editorial: The repair of DNA–protein crosslinks
por: Sun, Yilun, et al.
Publicado: (2023)

Lipid membrane interactions of self-assembling antimicrobial nanofibers: effect of PEGylation
por: Nielsen, Josefine Eilsø, et al.
Publicado: (2020)

Self-Assembly of Discrete Metal Complexes in Aqueous Solution via Block Copolypeptide Amphiphiles
por: Kuroiwa, Keita, et al.
Publicado: (2013)

Self-assembly of a helical zinc-europium complex: speciation in aqueous solution and luminescence
por: Deiters, Emmanuel, et al.
Publicado: (2013)

DNA-protein crosslinks are repaired via homologous recombination in mammalian mitochondria
por: Chesner, Lisa N., et al.
Publicado: (2020)

Electron attachment to DNA single strands: gas phase and aqueous solution
por: Gu, Jiande, et al.
Publicado: (2007)

High-resolution AFM structure of DNA G-wires in aqueous solution
por: Bose, Krishnashish, et al.
Publicado: (2018)

DNA-BOT: a low-cost, automated DNA assembly platform for synthetic biology
por: Storch, Marko, et al.
Publicado: (2020)

Monodisperse PEGylated Spheres: An Aqueous Colloidal Model System
por: Ulama, Jeanette, et al.
Publicado: (2014)

DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease
por: Reinking, Hannah K., et al.
Publicado: (2020)

Self-assembly of dengue virus empty capsid-like particles in solution
por: Neves-Martins, Thais C., et al.
Publicado: (2023)

Circuits and self-assembling DNA structures
por: Carbone, A, et al.
Publicado: (2002)

Molecular Tiling and DNA self-assembly
por: Carbone, A, et al.
Publicado: (2003)

Quantifying quality in DNA self-assembly
por: Wagenbauer, Klaus F., et al.
Publicado: (2014)

DNA interstrand crosslinking and sequence selectivity of dimethanesulphonates.
por: Ponti, M., et al.
Publicado: (1991)

DNA–protein crosslink proteases in genome stability
por: Ruggiano, Annamaria, et al.
Publicado: (2021)

Protection of nickel by self-assembled monolayers prepared in an aqueous self-emulsifying solution of a novel amphipathic organothiol
por: Yeyin, Tao, et al.
Publicado: (2023)

Self-Assembly of Temperature Sensitive Unilamellar Vesicles by a Blend of Block Copolymers in Aqueous Solution
por: Jang, Jong Dae, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lg8bk97a20foeaukut06vp9o6h