Maturation of GABAergic Transmission in Cerebellar Purkinje Cells Is Sex Dependent and Altered in the Valproate Model of Autism

Brain development is accompanied by a shift in gamma-aminobutyric acid (GABA) response from depolarizing-excitatory to hyperpolarizing-inhibitory, due to a reduction of intracellular chloride concentration. This sequence is delayed in Autism Spectrum Disorders (ASD). We now report a similar alterati...

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Detalles Bibliográficos
Autores principales: Roux, Sébastien, Lohof, Ann, Ben-Ari, Yehezkel, Poulain, Bernard, Bossu, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077203/
https://www.ncbi.nlm.nih.gov/pubmed/30104962
http://dx.doi.org/10.3389/fncel.2018.00232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077203/
https://www.ncbi.nlm.nih.gov/pubmed/30104962
http://dx.doi.org/10.3389/fncel.2018.00232

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