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Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

Objective: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative process affecting upper and lower motor neurons as well as non-motor systems. In this study, precentral and postcentral cortical thinning detected by structural magnetic resonance imaging (MRI) were combined with clini...

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Detalles Bibliográficos
Autores principales: Wirth, Anna M., Khomenko, Andrei, Baldaranov, Dobri, Kobor, Ines, Hsam, Ohnmar, Grimm, Thomas, Johannesen, Siw, Bruun, Tim-Henrik, Schulte-Mattler, Wilhelm, Greenlee, Mark W., Bogdahn, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077217/
https://www.ncbi.nlm.nih.gov/pubmed/30104996
http://dx.doi.org/10.3389/fneur.2018.00614