Biophysical, Biochemical, and Cell Based Approaches Used to Decipher the Role of Carbonic Anhydrases in Cancer and to Evaluate the Potency of Targeted Inhibitors

Carbonic anhydrases (CAs) are thought to be important for regulating pH in the tumor microenvironment. A few of the CA isoforms are upregulated in cancer cells, with only limited expression in normal cells. For these reasons, there is interest in developing inhibitors that target these tumor-associa...

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Detalles Bibliográficos
Autores principales: Mboge, Mam Y., Kota, Anusha, McKenna, Robert, Frost, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077552/
https://www.ncbi.nlm.nih.gov/pubmed/30112206
http://dx.doi.org/10.1155/2018/2906519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077552/
https://www.ncbi.nlm.nih.gov/pubmed/30112206
http://dx.doi.org/10.1155/2018/2906519

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