Bufadienolides from Venenum Bufonis Inhibit mTOR-Mediated Cyclin D1 and Retinoblastoma Protein Leading to Arrest of Cell Cycle in Cancer Cells

OBJECTIVE: Bufadienolides, the main components in Venenum Bufonis secreted from toads, have been proved to be with significant anticancer activity aside from the positive inotropic action as cardenolides. Here an underlying anticancer mechanism was further elucidated for an injection made from Venen...

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Detalles Bibliográficos
Autores principales: Chang, Huamei, Li, Juan, Cao, Yajun, Liu, Tiantian, Shi, Suofang, Chen, Wenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077658/
https://www.ncbi.nlm.nih.gov/pubmed/30108651
http://dx.doi.org/10.1155/2018/3247402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077658/
https://www.ncbi.nlm.nih.gov/pubmed/30108651
http://dx.doi.org/10.1155/2018/3247402

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