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In Silico Prediction of Large-Scale Microbial Production Performance: Constraints for Getting Proper Data-Driven Models
Industrial bioreactors range from 10.000 to 700.000 L and characteristically show different zones of substrate availabilities, dissolved gas concentrations and pH values reflecting physical, technical and economic constraints of scale-up. Microbial producers are fluctuating inside the bioreactors th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077756/ https://www.ncbi.nlm.nih.gov/pubmed/30105090 http://dx.doi.org/10.1016/j.csbj.2018.06.002 |