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Gambogic Acid and Its Analogs Inhibit Gap Junctional Intercellular Communication

Gap junctions (GJs) are intercellular channels composed of connexins. Cellular molecules smaller than 1 kDa can diffuse through GJs by a process termed gap junctional intercellular communication (GJIC), which plays essential roles in various pathological and physiological conditions. Gambogic acid (...

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Detalles Bibliográficos
Autores principales: Choi, Eun J., Yeo, Joo H., Yoon, Sei M., Lee, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077758/
https://www.ncbi.nlm.nih.gov/pubmed/30104974
http://dx.doi.org/10.3389/fphar.2018.00814