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Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

Genomic imprinting is an epigenetic mechanism leading to parent-of-origin silencing of alleles. So far, the precise number of imprinted regions in humans is uncertain. In this study, we leveraged genome-wide DNA methylation in whole blood measured longitudinally at three time points (birth, childhoo...

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Detalles Bibliográficos
Autores principales: Cuellar Partida, Gabriel, Laurin, Charles, Ring, Susan M, Gaunt, Tom R, McRae, Allan F, Visscher, Peter M, Montgomery, Grant W, Martin, Nicholas G, Hemani, Gibran, Suderman, Matthew, Relton, Caroline L, Davey Smith, George, Evans, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077796/
https://www.ncbi.nlm.nih.gov/pubmed/29860447
http://dx.doi.org/10.1093/hmg/ddy206