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TSPO–PET imaging using [(18)F]PBR06 is a potential translatable biomarker for treatment response in Huntington’s disease: preclinical evidence with the p75(NTR) ligand LM11A-31
Huntington’s disease (HD) is an inherited neurodegenerative disorder that has no cure. HD therapeutic development would benefit from a non-invasive translatable biomarker to track disease progression and treatment response. A potential biomarker is using positron emission tomography (PET) imaging wi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077813/ https://www.ncbi.nlm.nih.gov/pubmed/29860333 http://dx.doi.org/10.1093/hmg/ddy202 |