Self-organization of a human organizer by combined WNT and NODAL signalling

In amniotes, the development of the primitive streak (PS) and its accompanying “organizer” define the first stages of gastrulation. Despite detailed characterization in model organisms, the analogous human structures remain a mystery. We have previously shown that when stimulated with BMP4, micropat...

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Detalles Bibliográficos
Autores principales: Martyn, I., Kanno, T.Y., Ruzo, A., Siggia, E.D., Brivanlou, A.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077985/
https://www.ncbi.nlm.nih.gov/pubmed/29795348
http://dx.doi.org/10.1038/s41586-018-0150-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077985/
https://www.ncbi.nlm.nih.gov/pubmed/29795348
http://dx.doi.org/10.1038/s41586-018-0150-y

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