Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes

Studies of host genetic determinants of pathogen sequence variations can identify sites of genomic conflicts, by highlighting variants that are implicated in immune response on the host side and adaptive escape on the pathogen side. However, systematic genetic differences in host and pathogen popula...

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Detalles Bibliográficos
Autores principales: Naret, Olivier, Chaturvedi, Nimisha, Bartha, Istvan, Hammer, Christian, Fellay, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078058/
https://www.ncbi.nlm.nih.gov/pubmed/30105048
http://dx.doi.org/10.3389/fgene.2018.00266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078058/
https://www.ncbi.nlm.nih.gov/pubmed/30105048
http://dx.doi.org/10.3389/fgene.2018.00266

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