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Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes
Studies of host genetic determinants of pathogen sequence variations can identify sites of genomic conflicts, by highlighting variants that are implicated in immune response on the host side and adaptive escape on the pathogen side. However, systematic genetic differences in host and pathogen popula...
Autores principales: | Naret, Olivier, Chaturvedi, Nimisha, Bartha, Istvan, Hammer, Christian, Fellay, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078058/ https://www.ncbi.nlm.nih.gov/pubmed/30105048 http://dx.doi.org/10.3389/fgene.2018.00266 |
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