LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21

BACKGROUND: To explore potential therapeutic target is one of the areas of great interest in both clinical and basic hepatocellular carcinoma (HCC) studies. Nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) is proved to play a positive role in several cancers including breast cancer, pancreat...

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Detalles Bibliográficos
Autores principales: Xiao, Lijia, Wang, Yuliang, Liang, Weicheng, Liu, Liping, Pan, Nannan, Deng, Huimin, Li, Luqian, Zou, Chang, Chan, Franky Leung, Zhou, Yiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078084/
https://www.ncbi.nlm.nih.gov/pubmed/30122988
http://dx.doi.org/10.2147/CMAR.S162887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078084/
https://www.ncbi.nlm.nih.gov/pubmed/30122988
http://dx.doi.org/10.2147/CMAR.S162887

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