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Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis–Inflammatory Bowel Disease

B cells express an antigen‐specific B‐cell receptor (BCR) and may contribute to liver inflammation by recognizing shared antigens in the gut and liver. Herein, we used high‐throughput BCR sequencing of the immunoglobulin heavy chain, specifically the complementarity‐determining region 3 (CDR3), to c...

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Detalles Bibliográficos
Autores principales: Chung, Brian K., Henriksen, Eva Kristine Klemsdal, Jørgensen, Kristin Kaasen, Karlsen, Tom H., Hirschfield, Gideon M., Liaskou, Evaggelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078219/
https://www.ncbi.nlm.nih.gov/pubmed/30094406
http://dx.doi.org/10.1002/hep4.1200