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Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis–Inflammatory Bowel Disease
B cells express an antigen‐specific B‐cell receptor (BCR) and may contribute to liver inflammation by recognizing shared antigens in the gut and liver. Herein, we used high‐throughput BCR sequencing of the immunoglobulin heavy chain, specifically the complementarity‐determining region 3 (CDR3), to c...
Autores principales: | Chung, Brian K., Henriksen, Eva Kristine Klemsdal, Jørgensen, Kristin Kaasen, Karlsen, Tom H., Hirschfield, Gideon M., Liaskou, Evaggelia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078219/ https://www.ncbi.nlm.nih.gov/pubmed/30094406 http://dx.doi.org/10.1002/hep4.1200 |
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