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Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions
Oligomeric forms of the Aβ peptide represent the most probable neurotoxic agent in Alzheimer’s disease. The dynamic and heterogeneous character of these oligomers makes their structural characterization by classic methods difficult. Native mass spectrometry, when supported by additional gas phase te...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078298/ https://www.ncbi.nlm.nih.gov/pubmed/30080867 http://dx.doi.org/10.1371/journal.pone.0201761 |