Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease

In this study, we have investigated the effects of manganese superoxide dismutase (SOD2 or MnSOD) deficiency on mitochondrial function and oxidative stress during Chagas disease. For this, C57BL/6 wild type (WT) and MnSOD(+/-) mice were infected with Trypanosoma cruzi (Tc), and evaluated at 150 days...

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Detalles Bibliográficos
Autores principales: Wen, Jake J., Garg, Nisha Jain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078326/
https://www.ncbi.nlm.nih.gov/pubmed/30044789
http://dx.doi.org/10.1371/journal.pntd.0006687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078326/
https://www.ncbi.nlm.nih.gov/pubmed/30044789
http://dx.doi.org/10.1371/journal.pntd.0006687

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