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Characterisation of cellular effects of Burkholderia pseudomallei cycle inhibiting factor (Cif)
Cycle inhibiting factors (Cifs) are type III secretion system effectors produced by some Gram-negative pathogenic bacteria including Burkholderia pseudomallei. Through their deamidase activity, Cifs inhibit the activity of Cullin RING E3 ubiquitin ligases (CRL). CRL inhibition induces the accumulati...
Autores principales: | Ng, Mei Ying, Gan, Yunn-Hwen, Hagen, Thilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078346/ https://www.ncbi.nlm.nih.gov/pubmed/29848489 http://dx.doi.org/10.1242/bio.028225 |
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