Cargando…

HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Young-Eun, Lee, Minji, Gu, Hyejung, Kim, Jeongwoo, Jeong, Seongju, Yeo, Sujin, Lee, You Jeong, Im, Sin-Hyeog, Sung, Young-Chul, Kim, Hak Jae, Weissman, Irving L., Ahn, G-One
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078398/
https://www.ncbi.nlm.nih.gov/pubmed/29967068
http://dx.doi.org/10.1242/dmm.033241