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HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice
Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...
Autores principales: | Kim, Young-Eun, Lee, Minji, Gu, Hyejung, Kim, Jeongwoo, Jeong, Seongju, Yeo, Sujin, Lee, You Jeong, Im, Sin-Hyeog, Sung, Young-Chul, Kim, Hak Jae, Weissman, Irving L., Ahn, G-One |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078398/ https://www.ncbi.nlm.nih.gov/pubmed/29967068 http://dx.doi.org/10.1242/dmm.033241 |
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