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Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development

Schistosomiasis is a tropical disease caused by a flatworm trematode parasite that infects over 200 million people worldwide. Treatment and control of the disease rely on just one drug, praziquantel. The possibility of drug resistance coupled with praziquantel's variable efficacy encourages the...

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Detalles Bibliográficos
Autores principales: El-Sakkary, Nelly, Chen, Steven, Arkin, Michelle R., Caffrey, Conor R., Ribeiro, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078403/
https://www.ncbi.nlm.nih.gov/pubmed/29925529
http://dx.doi.org/10.1242/dmm.033563