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Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development
Schistosomiasis is a tropical disease caused by a flatworm trematode parasite that infects over 200 million people worldwide. Treatment and control of the disease rely on just one drug, praziquantel. The possibility of drug resistance coupled with praziquantel's variable efficacy encourages the...
Autores principales: | El-Sakkary, Nelly, Chen, Steven, Arkin, Michelle R., Caffrey, Conor R., Ribeiro, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078403/ https://www.ncbi.nlm.nih.gov/pubmed/29925529 http://dx.doi.org/10.1242/dmm.033563 |
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