Identification of cardioprotective drugs by medium-scale in vivo pharmacological screening on a Drosophila cardiac model of Friedreich's ataxia

Friedreich's ataxia (FA) is caused by reduced levels of frataxin, a highly conserved mitochondrial protein. There is currently no effective treatment for this disease, which is characterized by progressive neurodegeneration and cardiomyopathy, the latter being the most common cause of death in...

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Detalles Bibliográficos
Autores principales: Palandri, Amandine, Martin, Elodie, Russi, Maria, Rera, Michael, Tricoire, Hervé, Monnier, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078405/
https://www.ncbi.nlm.nih.gov/pubmed/29898895
http://dx.doi.org/10.1242/dmm.033811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078405/
https://www.ncbi.nlm.nih.gov/pubmed/29898895
http://dx.doi.org/10.1242/dmm.033811

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