Use of sodium 4-phenylbutyrate to define therapeutic parameters for reducing intracerebral hemorrhage and myopathy in Col4a1 mutant mice

Collagen type IV alpha 1 (COL4A1) and alpha 2 (COL4A2) form heterotrimers that constitute a major component of nearly all basement membranes. COL4A1 and COL4A2 mutations cause a multisystem disorder that includes variable cerebrovascular and skeletal muscle manifestations. The pathogenicity of COL4A...

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Detalles Bibliográficos
Autores principales: Hayashi, Genki, Labelle-Dumais, Cassandre, Gould, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078406/
https://www.ncbi.nlm.nih.gov/pubmed/29895609
http://dx.doi.org/10.1242/dmm.034157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078406/
https://www.ncbi.nlm.nih.gov/pubmed/29895609
http://dx.doi.org/10.1242/dmm.034157

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