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Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature
Regulation of autophagy by proteolytically cleaved fragments of heparan sulfate proteoglycans is a novel and current research focus in tumor biology. Endorepellin is the C-terminal angiostatic fragment of the heparan sulfate proteoglycan perlecan and induces autophagy in endothelial cells. To furthe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078466/ https://www.ncbi.nlm.nih.gov/pubmed/29921586 http://dx.doi.org/10.1074/jbc.RA118.002934 |