Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases

Reparative hepatocyte replication is impaired in chronic liver disease, contributing to disease progression; however, the underlying mechanism remains elusive. Here, we identify Map3k14 (also known as NIK) and its substrate Chuk (also called IKKα) as unrecognized suppressors of hepatocyte replicatio...

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Detalles Bibliográficos
Autores principales: Xiong, Yi, Torsoni, Adriana Souza, Wu, Feihua, Shen, Hong, Liu, Yan, Zhong, Xiao, Canet, Mark J, Shah, Yatrik M, Omary, M Bishr, Liu, Yong, Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078493/
https://www.ncbi.nlm.nih.gov/pubmed/30070632
http://dx.doi.org/10.7554/eLife.34152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078493/
https://www.ncbi.nlm.nih.gov/pubmed/30070632
http://dx.doi.org/10.7554/eLife.34152

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