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Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma

BRCA1-associated protein-1 (BAP1) is a nuclear localized deubiquitylating enzyme that belongs to the ubiquitin c-terminal hydrolase subfamily. The encoded protein is highly homologous between man and dogs, suggesting a functional significance preserved by evolution. BAP1 has multiple properties, inc...

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Detalles Bibliográficos
Autores principales: Jama, N., Farquhar, N., Butt, Z., Coupland, S.E., Sacco, J.J., Scase, T., Fielding, A.B., Coulson, J.M., Kalirai, H., Killick, D.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078709/
https://www.ncbi.nlm.nih.gov/pubmed/30060843
http://dx.doi.org/10.1016/j.jcpa.2018.06.007